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CSF2 — SCG2

Text-mined interactions from Literome

Harada et al., J Interferon Cytokine Res 2004 : We conclude that GM-CSF is a key molecule for cytokine induction by beta-glucan, and GM-CSF induction by SCG is the specific step in DBA/2 mice in vitro
Harada et al., J Interferon Cytokine Res 2006 : We recently found that the splenocytes from naive DBA/1 and DBA/2 mice are potently induced by SCG to produce interferon- gamma (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha), granulocyte-macrophage colony stimulating factor ( GM-CSF ), and interleukin-12p70 (IL-12p70), and that GM-CSF plays a key biologic role among these cytokines ... We concluded that induction of GM-CSF production by SCG was mediated through ICAM-1 and LFA-1 interaction, GM-CSF subsequently contributed to further cytokine induction by SCG, and reciprocal actions of the cytokines were essential for enhancement of the overall response to SCG in DBA/2 mice
Harada et al., Microbiol Immunol 2006 (Leukopenia) : The levels of interferon-(IFN-)gamma, tumor necrosis factor-(TNF-)alpha, granulocyte-macrophage-colony stimulating factor ( GM-CSF ), interleukin-(IL-) 6 and IL-12p70 were significantly increased by SCG in CY-treated mice