◀ Back to EPHB2
EPHB2 — MPST
Text-mined interactions from Literome
Lin et al., Oncogene 2001
(Cell Transformation, Neoplastic...) :
MST4 specifically
activates ERK but not JNK or p38 MAPK in transient transfected cells or in stable cell lines ... Overexpression of dominant negative MEK1 or treatment with PD98059 abolishes
MST4 induced
ERK activity, whereas dominant negative Ras or c-Raf-1 mutants failed to do so, indicating MST4 activates MEK1/ERK via a Ras/Raf-1 independent pathway
Hirai et al., J Biol Chem 1997
:
Both MUK/DLK/ZPK and MST/MLK2 cause a slight activation of p38/Mpk2 when overexpressed in COS-1 cells, whereas
MST/MLK2 , but not MUK/DLK/ZPK,
activates extracellular response kinase (ERK) to a certain degree