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NOS2 — UTP15

Text-mined interactions from Literome

Gendron et al., J Neurochem 2003 : Among the P2 receptor agonists tested, ATP, ADP, 2',3'-O- ( 4-benzoylbenzoyl ) -ATP ( BzATP ), and 2-methylthio-ATP ( 2-MeSATP ), but not UTP , enhanced IFN gamma induced iNOS expression and NO production, suggesting that the uridine nucleotide receptors P2Y2 and P2Y6 are not involved in this response
Chen et al., J Biol Chem 1998 : Taken together, these data demonstrate that nucleotides, especially UTP, can potentiate the LPS induced activation of NF-kappaB and AP-1 and of iNOS induction via a CaMK -dependent pathway and suggest that the UTP dependent up-regulation of iNOS may constitute a novel element in the inflammatory process