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IRF8 — NOS2

Text-mined interactions from Literome

Pavlovic et al., Eur Cytokine Netw 1999 : In conclusion, IRF-1 contributes to cytokine induced islet iNOS expression and cell death
Xiong et al., J Biol Chem 2003 : Overexpression of ICSBP greatly enhanced IFN-gamma induced iNOS promoter activation in RAW264.7 cells, and IFN-gamma induced iNOS promoter activation was abolished in ICSBP-/- macrophages ... In addition, interleukin-4 inhibits IFN-gamma induced iNOS gene expression by attenuating the physical interaction of ICSBP with IRF-1
De Stefano et al., J Mol Med (Berl) 2006 (Celiac Disease) : The role of NF-kappaB, IRF-1 , and STAT-1alpha transcription factors in the iNOS gene induction by gliadin and IFN-gamma in RAW 264.7 macrophages
Kamijo et al., Science 1994 (Tuberculosis) : Thus, IRF-1 is essential for iNOS activation in murine macrophages