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FGF10 — FGF21

Text-mined interactions from Literome

Acosta et al., Am J Physiol Lung Cell Mol Physiol 2001 : Exogenous FGF-10 not only stimulates FGF signaling, marked by increased mSpry2 expression, in both nitrofen treated and control lungs but also substantially rescues nitrofen induced lung hypoplasia in culture
Papadopoulou et al., Diabetes 2005 : We have earlier shown that the fibroblast growth factor ( FGF ) receptor 2 is expressed in pancreatic progenitor cells and that FGF10 , the high-affinity ligand of the FGF receptor 2 isoform FGF receptor 2b, promotes expansion of pancreatic progenitors
Kurosu et al., J Biol Chem 2007 : Accordingly, FGF19, but not FGF21 , activates FGF signaling in hepatocytes that primarily express FGFR4 and reduces transcription of CYP7A1 that encodes the rate limiting enzyme for bile acid synthesis
Kharitonenkov et al., J Cell Physiol 2008 : Interestingly, FGF-21 mediated effects are heparin independent suggesting that betaKlotho plays a role in FGF-21 activity similar to the one played by heparin in the signaling of conventional FGFs
Lü et al., Chin Med J (Engl) 2010 (Coronary Artery Disease) : Furthermore, FGF21 levels increased by 200 µmol/L bezafibrate could reduce CMECs apoptosis, and inhibit FGF21 expression by shRNA induced apoptosis ( P < 0.05 )
Adams et al., PloS one 2012 : The scaffold protein ßklotho ( KLB ) has previously been demonstrated in vitro to function as a co-factor permitting FGF21 mediated FGF receptor activation