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CDKN2B — SMAD7

Text-mined interactions from Literome

Feng et al., Mol Cell 2002 : Through its direct interaction with Smads, c-Myc binds to the Sp1-Smad complex on the promoter of the p15(Ink4B) gene, thereby inhibiting the TGF-beta induced transcriptional activity of Sp1 and Smad/Sp1 dependent transcription of the p15(Ink4B) gene
Gomis et al., Cancer Cell 2006 (Breast Neoplasms...) : We found the transcription factor C/EBPbeta to be essential for TGFbeta induction of the cell cycle inhibitor p15INK4b by a FoxO-Smad complex and repression of c-MYC by an E2F4/5-Smad complex in human epithelial cells