◀ Back to IRF6

IRF6 — NEU2

Text-mined interactions from Literome

Gee et al., J Biol Chem 2003 : Studies conducted to understand the role of MAPKs in the induction of sialidase activity revealed that LPS induced sialidase activity was dependent on p42/44 MAPK mediated TNF-alpha production ... Blocking TNF-alpha production by PD98059, a p42/44 inhibitor, significantly reduced the LPS induced sialidase activity and CD44-HA binding
Amith et al., Glycoconj J 2009 : Neuraminidase inhibitors BCX1827, 2-deoxy-2,3-dehydro-N-acetylneuraminic acid ( DANA ), zanamivir and oseltamivir carboxylate have a limited significant inhibition of the LPS induced sialidase activity in live BMC-2 macrophage cells but Tamiflu ( oseltamivir phosphate ) completely blocks this activity ... Tamiflu inhibits LPS induced sialidase activity in live BMC-2 cells with an IC ( 50 ) of 1.2 microM compared to an IC ( 50 ) of 1015 microM for its hydrolytic metabolite oseltamivir carboxylate ... Tamiflu blockage of LPS induced Neu1 sialidase activity is not affected in BMC-2 cells pretreated with anticarboxylesterase agent clopidogrel
Finlay et al., Glycoconj J 2010 (Mucolipidoses) : In contrast, the parent black seed oil ( BSO ) and another constituent of BSO para-cymene ( p-CY ) completely block LPS induced sialidase activity