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CA2 — IL6

Text-mined interactions from Literome

Carlstedt et al., Biosci Rep 1999 : Neither IL-6 nor TNF-alpha, affected cytoplasmic Ca2+ of the cells
Tokuda et al., Prostaglandins Leukot Essent Fatty Acids 1999 : The depletion of extracellular Ca2+ by EGTA reduced the PGD2 induced IL-6 synthesis
Junn et al., J Immunol 2000 : Requirement of hydrogen peroxide generation in TGF-beta 1 signal transduction in human lung fibroblast cells : involvement of hydrogen peroxide and Ca2+ in TGF-beta 1-induced IL-6 expression
Liu et al., Proc Soc Exp Biol Med 2000 (Calcium Signaling) : Ca2+ release from intracellular stores was strongly stimulated by acetylcholine (ACh) and ATP, but not by norepinephrine ( NA ), epidermal growth factor (EGF), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNFalpha)
Jeong et al., Cell Signal 2002 (Calcium Signaling) : These observations demonstrate that the intracellular Ca2+ may play an important role in IgE induced TNF-alpha and IL-6 secretion from mast cells via IKKbeta activation
Söderblom et al., Scand J Infect Dis 2003 (Inflammation) : Specifically, the proinflammatory cytokine interleukin-6 (IL-6) and chemokine IL-8 were induced by HlyA induced Ca2+ oscillations
Lee et al., Proc Natl Acad Sci U S A 2003 (Calcium Signaling) : These findings support a model in which Ca2+ binding to the C-terminal EF-hands of preassociated CaM initiates CDF via interaction with the IQ-like domain
Tanaka et al., Eur J Immunol 2005 : Ca2+ influx mediated histamine synthesis and IL-6 release in mast cells activated by monomeric IgE
Zi et al., Zhonghua Nan Ke Xue 2006 : IL-6 could induce AR by stimulating the activity of acrosin and SOD in human sperm, which also involves the activation of PKC, and requires the presence of extracellular Ca2+
Keller et al., Cytokine 2006 : Here we investigated whether skeletal myocytes produce IL-6 in a Ca2+/calcineurin dependent manner, and whether TNF-alpha, an inducer of IL-6, is affected by these stimuli
Nie et al., J Physiol Sci 2007 (Calcium Signaling...) : We confirmed that a high-K ( + ) and high-Ca(2) ( + ) could induce an increase of the intracellular Ca ( 2+ ) concentration and subsequent CDF and CDI
Wang et al., J Biol Chem 2009 (Calcium Signaling) : Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1 induced Ca2+ signaling
Kodama et al., Meikai Daigaku Shigaku Zasshi 1990 (Bone Resorption...) : Among several bioactive substances known as coupling factors, transforming growth factor-beta ( TGF-beta ), interleukin-1 (IL-1), and prostaglandin ( PG ) E1 and E2 increased not only the activity of alkaline phosphatase but also the rate of incorporation of 45Ca2+ into ROS 17/2.8 during a 3-day culture : the former two factors are known to be formed at the site where bone is resorbed, while PG 's are known as one of the factors involved in bone resorption
Kodama et al., Meikai Daigaku Shigaku Zasshi 1989 (Bone Resorption) : The effects of interleukin 1, transforming growth factor-beta ( coupling factors ), prostaglandin E1, and prostaglandin E2 on incorporation of 45Ca2+ and on alkaline phosphatase activity were studied using cultured ROS 17/2.8 cells, one of cell lines derived from rat osteosarcoma
Qiu et al., Biochem Pharmacol 1994 : In the present study, we investigated the effects of lymphokines [interleukin-4 (IL-4), interleukin-2 (IL-2) ] and other pharmacologic agents [ lipopolysaccharide (LPS), phorbol 12-myristate 13-acetate ( PMA ) ] on HTMT induced Ca2+ and IP responses in non rosetted cells
de Wit et al., Br J Haematol 1994 : Using the human monocytic cell line Mono Mac 6 we studied the involvement of Ca2+ , protein kinase A (PKA), and protein kinase C ( PKC ) dependent pathways in the regulation of M-CSF and IL-6 gene expression
Kozawa et al., Arch Biochem Biophys 1997 : The depletion of extracellular Ca2+ by EGTA suppressed the thrombin induced IL-6 synthesis
Kumar et al., Int J Immunopharmacol 1997 : Effect of prolactin on nitric oxide and interleukin-1 production of murine peritoneal macrophages : role of Ca2+ and protein kinase C
Kozawa et al., Cell Signal 1997 : The depletion of extracellular Ca2+ by EGTA suppressed the bFGF induced IL-6 synthesis
Kozawa et al., Bone 1998 : The depletion of extracellular Ca2+ by EGTA reduced the PGE2 induced IL-6 secretion
Adebanjo et al., J Cell Biol 1998 (Bone Resorption) : Additionally, IL-6 ( 5 pg/l to 10 microg/l ) inhibited cytosolic Ca2+ signals triggered by high Ca2+ or Ni2+ ... Thus, while high Ca2+ enhances IL-6 secretion, the released IL-6 attenuates Ca2+ sensing and reverses inhibition of resorption by Ca2+