Weernink et al., J Biol Chem 2004
:
Here we show that RhoA and Rac1, as well as Cdc42, but not the Ras-like GTPases, RalA and Rap1A, markedly stimulate PIP ( 2 ) synthesis by all three PIP5K isoforms expressed in human embryonic kidney 293 cells, both in vitro and in vivo
Van Keymeulen et al., J Cell Biol 2006
:
Cdc42 mediates PIP3 's positive effect on RhoA activity