◀ Back to BCR

BCR — MAPKAPK2

Text-mined interactions from Literome

Swart et al., J Immunol 2000 (Lymphoma, B-Cell...) : BCR cross linking also led to increased MAPK activated protein kinase-2 activity, an enzyme that lies immediately downstream from p38 MAPK ; MAPK activated protein kinase-2 immune complexes phosphorylated a peptide substrate containing the CREB serine 133 phosphoacceptor motif
Salmon et al., J Immunol 1997 : Cross linking of the B cell Ag receptor (BCR) or CD40 on freshly isolated or LPS activated splenic B cells or the immature B lymphoma, WEHI 231, resulted in activation of p38 MAPK and MAPKAP kinase-2 ... We conclude that the activation of p38 MAPK and MAPKAP kinase-2 by cross linking of the TCR, BCR , Fas, or CD40 was not correlated with their roles in regulating lymphocyte survival, and that suppression of kinase activity did not inhibit the induction of apoptosis