Gene interactions and pathways from curated databases and text-mining

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LDLR — NUP43

Text-mined interactions from Literome

Singh et al., J Biol Chem 1999 : SB202190 dependent increase in LDL receptor expression was accompanied by induction of p42/44(MAPK) , and inhibition of this pathway completely prevented SB202190 induced LDL receptor expression, suggesting that p38 ( MAPK ) negatively regulates the p42/44(MAPK) cascade and the responses mediated by this kinase
Kapoor et al., J Lipid Res 2003 : pp90RSK- and protein kinase C-dependent pathway regulates p42/44MAPK induced LDL receptor transcription in HepG2 cells ... The present studies were designed to delineate the molecular mechanisms underlying p42/44MAPK induced LDL receptor transcription in HepG2-Delta Raf-1 : ER cells, a modified HepG2 cell line in which the Raf-1/MEK/p42/44MAPK cascade can be specifically activated by anti-estradiol ICI182,780 in an agonist-specific manner
Kumar et al., J Lipid Res 1997 : Phorbol ester induced low density lipoprotein receptor gene expression in HepG2 cells involves protein kinase C-mediated p42/44 MAP kinase activation