Gene interactions and pathways from curated databases and text-mining

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BRCA1 — NEK2

Text-mined interactions from Literome

Wang et al., J Biol Chem 2004 (Genomic Instability...) : We demonstrate that small interfering RNA mediated suppression of Brca1 decreased Nek2 more dramatically in Gadd45a ( -/- ) cells than in wild-type cells and, conversely, that overexpression of Brca1 and/or Gadd45a up-regulated transcription of Nek2
Sankaran et al., Cancer Res 2007 : We show that Aurora-A kinase modulates the BRCA1 inhibition of centrosome function by decreasing the E3 ubiquitin ligase activity of BRCA1