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MAP3K1 — MAP4K2

Pathways - manually collected, often from reviews:

• BioCarta role of mal in rho-mediated activation of srf: MAP4K2 → MEKK1 (MAP3K1) (modification, activates)
• NCI Pathway Database TNF receptor signaling pathway : Group I GCKs (MAP4K2/NRK/MAP4K5/MAP4K4/TNIK/MAP4K3) → MEKK1 (MAP3K1) (modification, activates) Yuasa et al., J Biol Chem 1998*
  Evidence: mutant phenotype, physical interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: MAP3K1 — MAP4K2 Yuasa et al., J Biol Chem 1998*
• IRef Bind_translation Interaction: MAP3K1 — MAP4K2 (experimental interaction detection) Yuasa et al., J Biol Chem 1998*
• IRef Bind_translation Interaction: MAP3K1 — MAP4K2 (affinity chromatography technology) Yuasa et al., J Biol Chem 1998*
• IRef Biogrid Interaction: MAP4K2 — MAP3K1 (physical association, affinity chromatography technology) Chadee et al., Mol Cell Biol 2002*
• IRef Biogrid Interaction: MAP4K2 — MAP3K1 (direct interaction, pull down) Yuasa et al., J Biol Chem 1998*
• IRef Intact Interaction: MAP4K2 — MAP3K1 (physical association, anti bait coimmunoprecipitation) Chadee et al., Mol Cell Biol 2002*