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CDH2 — WNT2

Text-mined interactions from Literome

Stewart et al., J Biol Chem 2000 : These results indicate that the level of cadherin-6 , but not that of E-cadherin, is strictly regulated post-translationally in response to Wnt signaling, and that E-cadherin and cadherin-6 may contribute different properties to cell-cell adhesion and the epithelial phenotype
Rodríguez-Esteban et al., Development 2001 : Both the adhesion protein N-cadherin and PKI ( an endogenous protein kinase A inhibitor ) are localized to the right side of the node and may contribute to restrict Nodal activation by Wnt signaling and PKA to the left side of the node
Ohira et al., Proc Natl Acad Sci U S A 2003 (Lung Neoplasms) : Drosophila DE-cadherin is regulated by Wnt/beta-catenin signaling, although this has not been demonstrated in mammalian cells
Brembeck et al., Genes Dev 2004 : beta-Catenin controls both cadherin mediated cell adhesion and activation of Wnt target genes
Obara et al., Methods Mol Biol 2006 (Cell Transformation, Neoplastic) : beta-catenin seems to link cadherin mediated cell-cell adhesion and Wnt signaling
Sarrió et al., Hum Pathol 2006 (Adenocarcinoma...) : Alterations in the cadherin-catenin expression and activation of the Wnt signaling have been related to the pathology of ovarian carcinomas
Kreslova et al., Genesis 2007 (Choristoma...) : beta-Catenin plays a key role in cadherin mediated cell adhesion as well as in canonical Wnt signaling
Haÿ et al., Mol Cell Biol 2009 : We show here a novel mechanism by which the adhesion molecule N-cadherin interacts with the Wnt coreceptor LRP5 and regulates canonical Wnt/beta-catenin signaling in osteoblasts ... These data indicate that a previously unrecognized N-cadherin-axin-LRP5 interaction negatively regulates Wnt/beta-catenin signaling and is critical in the regulation of osteoblast function, bone formation, and bone mass
Nygren et al., Exp Hematol 2009 (Leukemia, B-Cell...) : beta-catenin is involved in N-cadherin dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1 positive B acute lymphoblastic leukemia cells
Heuberger et al., Cold Spring Harbor perspectives in biology 2010 : Interplay of cadherin mediated cell adhesion and canonical Wnt signaling ... beta-Catenin is an essential molecule both in cadherin mediated cell adhesion and in canonical Wnt signaling
Chalpe et al., Cell Adh Migr 2010 : This project was initiated to investigate the role of canonical Wnt signaling in the expression of cadherin-7 and cadherin-11 by treating neural crest cells with Wnt3a ligand
Kim et al., Biomaterials 2010 : It was found that cell aggregation was promoted on this surface, supporting the notion that an increase in N-cadherin mediated cell-cell contacts and Wnt signaling regulate hMSC differentiation into cardiomyocyte-like cells
Xu et al., J Biol Chem 2011 : To further explore the molecular mechanism of this regulation, the roles of ß-catenin, an essential molecule in both cadherin mediated cell adhesion and canonical Wnt signaling, were investigated
Howard et al., PloS one 2011 (Wnt Signaling Pathway) : A positive role of cadherin in Wnt/ß-catenin signalling during epithelial-mesenchymal transition
Haÿ et al., J Bone Miner Res 2012 (Wnt Signaling Pathway) : Peptide based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation ... We also show that the peptide mediated disruption of N-cadherin-LRP5/6 interaction increases Wnt/ß-catenin signaling and osteoblast function in vitro and promotes calvaria bone formation in vivo
Sengupta et al., J Cell Sci 2013 : Transfection of hypoglycosylated E-cadherin mutant, V13, but not fully N-glycosylated E-cadherin , into sparse cells inhibited canonical Wnt activity by depleting nuclear ß- and ?-catenins
Grossmann et al., Science signaling 2013 (Melanoma...) : We found that in melanoma cells, WNT5A stimulated the disruption of N-cadherin and ß-catenin complexes by activating the guanosine triphosphatase adenosine diphosphate ribosylation factor 6 ( ARF6 )
Hadeball et al., Mech Dev 1998 : Xenopus cadherin-11 ( Xcadherin-11 ) expression requires the Wg/Wnt signal