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CCND2 — TNFSF13B
Text-mined interactions from Literome
Moreaux et al., Haematologica 2007
(Multiple Myeloma) :
Triggered by the finding that TACI and c-maf expressions correlate in TACI+ HMCL, we demonstrated that TACI activation influences c-maf expression : ( i ) activation of TACI by
BAFF or APRIL
increases c-maf, cyclin D2, and integrin beta7 gene expressions in TACI+ HMCL, ( ii ) blocking of autocrine BAFF/APRIL stimulation in some TACI+ HMCL by the TACI-Fc fusion protein reduces c-maf,
cyclin D2 , and integrin beta7 gene expression, ( iii ) nucleofection of siRNA to c-maf decreases c-maf mRNA levels and reduces the expression of cyclin D2 and integrin beta7 gene expressions, without affecting TACI expression
Ji et al., Biochem Biophys Res Commun 2012
:
BAFF induces spleen CD4+ T cell proliferation by down regulating phosphorylation of FOXO3A and
activates cyclin D2 and D3 expression