Gene interactions and pathways from curated databases and text-mining

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CA2 — HSP90AA1

Text-mined interactions from Literome

Edlich et al., J Biol Chem 2007 : The Bcl-2 regulator FKBP38-calmodulin-Ca2+ is inhibited by Hsp90
Nishida et al., J Biol Chem 1986 : Here we show that calmodulin regulates the binding of HSP90 to F-actin in a Ca2+ dependent manner ... Calmodulin was found to inhibit the binding of HSP90 to F-actin in a Ca2+ dependent manner ... Moreover, the equilibrium gel filtration demonstrated that calmodulin binds to HSP90 in the presence of Ca2+ , but not in the absence of Ca2+ ... Ca2+ dependent interaction of HSP90 with calmodulin as well as calmodulin regulated binding of HSP90 to F-actin revealed here may provide new insight into the function of HSP90 and the regulation of actin structure in cells