Ferreira et al., Mem Inst Oswaldo Cruz 2012
(Chronic Disease...) :
We demonstrate that stimulation with SEA induced prominent lymphocyte proliferation and high levels of tumour necrosis factor (TNF)-a, interleukin (IL)-4 and IL-10 secretion in both OST and non infected individuals ( NI )
Hobeika et al., Biochem Biophys Res Commun 1996
:
A synthetic peptide of this region, SEA ( 121-149 ), blocks SEA binding to class II MHC molecules and induces interleukin-1 and tumor necrosis factor production in monocytes
Fujisawa et al., J Immunol 1998
:
The accumulation of IL-8 in the culture medium of HMVEC-L was increased by SEA in a dose dependent manner and was directly related to the number of PBMCs present