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HGF — IGF1

Text-mined interactions from Literome

Grunnet et al., J Hepatol 1999 : In subconfluent culture hepatocyte growth factor increased the DNA synthesis rate 6-fold, epidermal growth factor 3-fold, and insulin-like growth factor-I 2-fold ; that of albumin, urea and glucose was not increased significantly
Sheehan et al., J Cell Physiol 1999 : In proliferating cultures of satellite cells, HGF , insulin-like growth factor I (IGF-I) and FGF1 stimulated significantly ( P < 0.05 ) higher levels of FGFR1 message content, relative to control conditions, and platelet derived growth factor-BB ( PDGF-BB ) and insulin-like growth factor ( IGF-II ) significantly ( P < 0.05 ) depressed FGFR1 expression
Skrtic et al., Endocrinology 1999 : It has been shown recently that insulin-like growth factor 1 (IGF-1) increases both DNA synthesis and hepatocyte growth factor (HGF) production in cultured hepatic stellate cells ... Both LY 294002 and PD 98059 lowered the IGF-1 induced increase of HGF in the medium by about 40 %, but LY 294002 was 10 times more potent than PD 98059 ... Inhibition of p70S6K activation by rapamycin blocked IGF-1 induced DNA synthesis but not the increase in HGF
Skrtic et al., Horm Res 2001 (Liver Diseases) : Studies on cultured rat hepatic stellate cells (HSC) showed that IGF-1 and hepatocyte conditioned medium ( PCcM ) time- and dose-dependently increased hepatocyte growth factor (HGF) mRNA and HGF immunoreactivity ... The in vitro results indicate that both IGF-1 and IGF- 1-independent factor ( s ) from hepatocytes can stimulate HGF production by HSC
Ekberg et al., J Endocrinol 1992 : In the present study, the effects of GH and insulin-like growth factor-I (IGF-I) on HGF gene expression in regenerating rat liver was investigated
de Jong et al., Scand J Gastroenterol 2004 (Colorectal Neoplasms...) : PH is associated with a lower acute-phase and total IGF-I response and a higher HGF and IL-6 response compared with laparotomy
Bauer et al., Ann Surg 2005 (Colorectal Neoplasms...) : To determine whether insulinlike growth factor-I (IGF-I) and hepatocyte growth factor (HGF) cooperate to induce migration and invasion of human colorectal carcinoma ( CRC ) cells and whether the effects of IGF-I and/or HGF are mediated through activation of the urokinase plasminogen activator (uPA)/uPA receptor ( uPAR ) system, a central mediator of tumor-cell migration and invasion