Gene interactions and pathways from curated databases and text-mining

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IFI44 — JAK2

Text-mined interactions from Literome

Yamashita et al., J Biol Chem 1999 (Lymphoma, T-Cell) : Short term incubation ( < 60 min ) of prolactin-responsive Nb2 lymphoma cells at high density selectively blocked prolactin stimulation of p42/p44 mitogen activated protein kinases and transcription factors Stat1 and Stat3 but not prolactin activation of Stat5 or the tyrosine kinase Jak2
Majka et al., Exp Hematol 2002 (MAP Kinase Signaling System) : Further, in an attempt to correlate the influence of these factors on cell proliferation and survival with activation of signal transduction pathways, we evaluated their effect on the phosphorylation of MAPK p42/44 and activation of PI-3K-AKT and JAK-STAT proteins in these various cell types