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ICOSLG — IL21
Text-mined interactions from Literome
Wahl et al., J Am Soc Nephrol 2002
:
Interestingly,
interleukin-2 production by T cell hybridomas after antigen presentation by TEC was
enhanced by blocking antibodies to
B7RP-1 and ICOS
de Haij et al., Kidney Int 2005
:
Stimulation with interferon-gamma (IFN-gamma) resulted in increased expression of B7-H1, whereas
ICOS-L expression was marginally
increased upon stimulation with CD40L, with no effect of
interleukin ( IL-1 ), IL-17, or tumor necrosis factor-alpha (TNF-alpha)
Nurieva et al., Immunity 2008
:
Tfh cell generation was regulated by
ICOS ligand (ICOSL) expressed on B cells and was
dependent on
interleukin-21 (IL-21) , IL-6, and signal transducer and activator of transcription 3 ( STAT3 )
Penel-Sotirakis et al., PloS one 2012
:
IL-21 and IL-22 production were dependent on the B7/CD28 co-stimulatory pathway and
ICOS-L expression on skin LCs significantly
reduced IL-21 level