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IRF6 — SCARB1

Text-mined interactions from Literome

Hullinger et al., J Biol Chem 2001 : Transient transfection studies demonstrated that LPS represses SR-BI promoter activity in the macrophage cell line RAW 264.7
Baranova et al., Infect Immun 2002 : In addition, we compared the potencies of various modified LPS preparations and demonstrated that the phosphorylated lipid A portion of LPS, which is highly conserved among gram negative microorganisms, including Chlamydia, is primarily responsible for the effects of LPS on SR-B1 and ABCA1 expression ... Inhibitors of NF-kappaB activation were observed to efficiently block the suppressive effect of LPS on SR-B1 and ABCA1, suggesting a mechanism involving NF-kappaB
Huang et al., J Cell Biochem 2010 : LPS induced SR-B1 and StAR protein expression are abolished by TLR2 blocker ... Those inhibitors of PI(3)K/Akt pathways also abolish LPS induced aldosterone secretion and SR-B1 protein level ... In conclusion, LPS induced aldosterone production and SR-B1 proteins expression are through the TLR2 and TLR4 related PI(3)K/Akt pathways in adrenal ZG cells