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C1QB — IRF6

Text-mined interactions from Literome

Zhang et al., Immunopharmacology 1999 (Hemolysis) : Lectin pathway activation also enhances the antibody independent C activation of the classical C pathway via C1q by ReLPS, as well as the direct activation of the alternative C pathway by wild type LPS
Zhou et al., J Leukoc Biol 1991 : Our findings indicate that LPS as well as FcR and C3bR triggering agents stimulate early and sustained C1q synthesis accompanied by an early and short lived burst of C1q secretion which rapidly diminished and results in an increased intracellular accumulation of C1q due to ongoing synthesis ... Our results suggest that LPS , IC, and AZ alone or in combination with IFN-gamma stimulate early C1q production to modulate macrophage effector functions followed by an inhibition of C1q secretion when the activation process has been culminated