Gene interactions and pathways from curated databases and text-mining

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FOXP3 — PIK3R1

Text-mined interactions from Literome

Merkenschlager et al., J Exp Med 2010 : These studies therefore explain the negative regulation of Foxp3 by PI3K signaling, and add Foxo proteins to the growing list of nuclear factors capable of modulating Foxp3 expression
Dutra et al., Br J Pharmacol 2011 (Colitis) : Importantly, the PI3K? inhibitor also up-regulated IL-10, CD25 and FoxP3 expression