Gene interactions and pathways from curated databases and text-mining

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EPHB2 — ITGB1

Text-mined interactions from Literome

Wilson et al., Invest Ophthalmol Vis Sci 2003 : Fibronectin fragments promote human retinal endothelial cell adhesion and proliferation and ERK activation through alpha5beta1 integrin and PI 3-kinase
Brockbank et al., Br J Cancer 2005 (Carcinoma, Squamous Cell...) : However, integrin beta1 is not required for cell growth or activation of FAK and ERK signalling in vitro or in vivo
Basu et al., FEBS Lett 2007 : We demonstrate that heregulin activated MSK1/2 and phosphorylated histone H3 at serine 10 in cultured C2C12 muscle cells, in an ERK dependent manner
Tyagi et al., Mol Cell Biochem 2008 (Cardiovascular Diseases) : In cultured ECs, Fg binding to intercellular adhesion molecule-1 and to alpha(5)beta(1) integrin , caused phosphorylation of ERK
McGilvray et al., J Biol Chem 1997 : Inhibition of tyrosine kinase activity with genistein ( 10 microg/ml ) as well as selective MAP kinase inhibition with the MEK-1 inhibitor PD98059 abolished the VLA-4 dependent ERK tyrosine phosphorylation, inhibited NF kappaB nuclear binding, and abrogated tissue factor expression induced by both VLA-4 cross linking and adhesion to fibronectin in THP-1 cells and human peripheral blood monocytes