Gene interactions and pathways from curated databases and text-mining

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GRAP2 — IFNG

Text-mined interactions from Literome

Chan et al., Am J Physiol Cell Physiol 2001 : We found that extracellular signal regulated kinase ( ERK ) augmented and p38 ( mapk ) inhibited IFN-gamma + LPS induction of iNOS
Mavropoulos et al., Blood 2005 : Therefore, the synergistic induction of IFN-gamma by IL-12 and IL-18 in natural killer cells is mediated at least in part by p38 dependent and 3 ' UTR mediated stabilization of IFN-gamma mRNA
Fukushima et al., J Neuroimmunol 2005 (MAP Kinase Signaling System...) : We analyzed the relationship between the expression of interferon (IFN)-gamma and HTLV-I p19 antigen and activation of p38 mitogen activated protein kinase ( p38 MAPK ) in two HTLV-I infected T cell lines derived from two patients ( HCT-1 and HCT-4 ) with HTLV-I associated myelopathy/tropical spastic paraparesis ( HAM/TSP ), and three HTLV-I infected T cell lines derived from three patients with adult T cell leukemia ( ATL )
Sodhi et al., Glycoconj J 2007 : Pharmacological inhibitor of tyrosine kinase, PI3 kinase, protein kinase C, p42/44, p38 , JNK and intracellular calcium immobilizing agent down regulated the WGA induced expression of cytokines TNF-alpha, IL-1beta, IL-12 and IFN-gamma
Magrone et al., Curr Pharm Des 2008 (Chronic Disease...) : In particular, it seems that p38 , a molecule belonging to the MAPK family, is involved in the release of IFN-gamma and, therefore, in NO production