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IL4 — ITIH4
Text-mined interactions from Literome
del Real et al., Mol Immunol 1999
:
Anti-gp120 antibody production in nude mice is
mediated principally by GM-CSF/gp120 triggered
IL-4 production, since neutralizing anti-IL-4 abrogates the in vivo response
Patella et al., J Immunol 2000
:
HIV-1
gp120 induces
IL-4 and IL-13 release from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE ... The average t1/2
gp120 induced
IL-4 release was lower than for IL-13 release ... Basophils from which IgE had been dissociated by brief exposure to lactic acid no longer released
IL-4 in
response to
gp120 or to anti-IgE ... Three human VH3+ monoclonal IgM inhibited
gp120 induced secretion of
IL-4 from basophils ... In contrast, VH6+ monoclonal IgM did not inhibit the release of
IL-4 induced by
gp120
Marone et al., Immunol Rev 2001
(HIV Infections) :
Gp120 also
induces IL-4 and IL-13 synthesis from basophils
Marone et al., Int Arch Allergy Immunol 2001
(HIV Infections) :
gp120 also
induces IL-4 and IL-13 synthesis in human basophils
Faith et al., Clin Exp Immunol 1996
:
Neither
gp120 nor the CD4 binding region peptide
had any effect on
IL-4 production by the T cell lines
Taoufik et al., Blood 1997
:
Human immunodeficiency virus
gp120 inhibits
interleukin-12 secretion by human monocytes : an indirect interleukin-10 mediated effect
Capobianchi et al., J Biol Regul Homeost Agents 1996
(Acquired Immunodeficiency Syndrome) :
However, neither
IL-4 ( Th2-type ) nor IL-2 ( Th1-type ), nor DNA synthesis are
activated by
gp120