Gene interactions and pathways from curated databases and text-mining

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IL4 — ITIH4

Text-mined interactions from Literome

del Real et al., Mol Immunol 1999 : Anti-gp120 antibody production in nude mice is mediated principally by GM-CSF/gp120 triggered IL-4 production, since neutralizing anti-IL-4 abrogates the in vivo response
Patella et al., J Immunol 2000 : HIV-1 gp120 induces IL-4 and IL-13 release from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE ... The average t1/2 gp120 induced IL-4 release was lower than for IL-13 release ... Basophils from which IgE had been dissociated by brief exposure to lactic acid no longer released IL-4 in response to gp120 or to anti-IgE ... Three human VH3+ monoclonal IgM inhibited gp120 induced secretion of IL-4 from basophils ... In contrast, VH6+ monoclonal IgM did not inhibit the release of IL-4 induced by gp120
Marone et al., Immunol Rev 2001 (HIV Infections) : Gp120 also induces IL-4 and IL-13 synthesis from basophils
Marone et al., Int Arch Allergy Immunol 2001 (HIV Infections) : gp120 also induces IL-4 and IL-13 synthesis in human basophils
Faith et al., Clin Exp Immunol 1996 : Neither gp120 nor the CD4 binding region peptide had any effect on IL-4 production by the T cell lines
Taoufik et al., Blood 1997 : Human immunodeficiency virus gp120 inhibits interleukin-12 secretion by human monocytes : an indirect interleukin-10 mediated effect
Capobianchi et al., J Biol Regul Homeost Agents 1996 (Acquired Immunodeficiency Syndrome) : However, neither IL-4 ( Th2-type ) nor IL-2 ( Th1-type ), nor DNA synthesis are activated by gp120