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TG — TNF

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Wang et al., Cancer 2002 (Carcinoma...) : TNF-alpha also induced increased thyroglobulin secretion and reduced VEGF secretion by anaplastic tumor cells
Wang et al., J Clin Endocrinol Metab 2003 (Carcinoma...) : Recently, we found that TNFalpha induces cytomorphological differentiation in anaplastic thyroid cancer cells and increases thyroglobulin expression ; however, TNF is cytotoxic for normal human tissue
Rasmussen et al., J Endocrinol 1994 : In the present study, TNF-alpha , TNF-beta and IFN-gamma all inhibited thyroglobulin (Tg) and cAMP production from cultured human thyroid cells
Tang et al., Endocrinology 1995 : In the present study, we used FRTL5 cells, a cultured rat thyroid follicular cell line, to examine the effects of IFN-gamma and TNF-alpha on type I 5'-deiodinase ( 5'D-I ) activity and 5'D-I, thyroid peroxidase (TPO) and thyroglobulin (Tg) gene expression
Resetkova et al., Clin Invest Med 1993 (Graves Disease...) : We have investigated the in vitro effects of interleukin-1-beta (IL-1-beta), interleukin-2 (IL-2), tumor necrosis factor-alpha (TNF-alpha) , and interferon-gamma (IFN-gamma) on the induction of anti-thyroperoxidase ( anti-TPO ), anti-thyroglobulin ( anti-Tg ), and IgG secreting cells ( SC ) by cultures of pokeweed mitogen ( PWM ) -stimulated peripheral blood mononuclear cells ( PBMC ) obtained from patients with Hashimoto 's thyroiditis ( HT ), Graves ' disease ( GD ), and controls ( C )