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CD28 — FOS
Text-mined interactions from Literome
Kempiak et al., J Immunol 1999
:
Dominant negative versions of JNK kinase, c-Jun, and IKK beta interfered In CD3- plus
CD28 induced
CD28RE/AP-1 luciferase activity in Jurkat cells
Olsson et al., J Biol Chem 1999
:
CTLA-4 ligation suppresses
CD28 induced NF-kappaB and
AP-1 activity in mouse T cell blasts
Coudronniere et al., Proc Natl Acad Sci U S A 2000
:
Fourth,
CD3/CD28 induced
CD28RE/AP-1 activation and NF-kappaB nuclear translocation were blocked by a selective PKCtheta inhibitor
Li et al., EMBO J 2004
:
Conversely, a SPAK-specific RNAi or a dominant negative SPAK mutant inhibited PKCtheta- and
TCR/CD28 induced
AP-1 , but not NF-kappaB, activation
Puzik et al., Cytokine 2012
(Infection) :
While IGF-I did not influence apoptosis in our experimental setting, it led to a distinct decrease in
anti-CD3/CD28 stimulated DNA binding activity of
AP-1 and NF?B
Los et al., Biochem J 1994
:
Inhibition of
activation of transcription factor
AP-1 by
CD28 signalling in human T-cells
Edmead et al., J Immunol 1996
:
Induction of
activator protein (AP)-1 and nuclear factor-kappaB by
CD28 stimulation involves both phosphatidylinositol 3-kinase and acidic sphingomyelinase signals ... Using selective inhibitors, we investigated the signaling pathways involved in the
CD28 mediated induction of
AP-1 and NF-kappaB
Gringhuis et al., Blood 1997
(Leukemia-Lymphoma, Adult T-Cell) :
T-cell receptor (TCR)/CD3 engagement results in the activation of nuclear factor of activated T cells ( NFAT ),
activator protein-1 (AP-1) , and nuclear factor kappaB (NFkappaB), whereas the CD28 responsive complex (CD28RC) is activated in
response to the
CD28 signal