◀ Back to APOB

APOB — SELP

Text-mined interactions from Literome

Klouche et al., Arterioscler Thromb Vasc Biol 1999 (Arteriosclerosis) : In endothelial cells, E-LDL stimulated upregulation of intercellular adhesion molecule-1 ( ICAM-1 ), platelet-endothelial cells adhesion molecule-1 ( PECAM-1 ), P-selectin , and E-selectin with distinct kinetics
Zhao et al., Thromb Res 2000 : The present study assessed the effects of native and oxidized LDL ( n-LDL and ox-LDL ) and Lp(a) ( n-Lp(a) and ox-Lp(a) ) on the expression of P-selectin in cultured human umbilical vein endothelial cells ( HUVECs ) ... Results showed that P-selectin protein expression was not influenced by n-LDL, but was moderately increased by ox-LDL and n-Lp(a)
Chen et al., Circ Res 2001 : Ox-LDL also enhanced the expression of P-selectin and ICAM-1 as well as monocyte adhesion to HCAECs ( P < 0.05 versus control untreated cells )
Liu et al., Acta Pharmacol Sin 2002 : PBC at 10 to 80 micromol/L inhibited Ox-LD L-induced adhesion index from 16.7 % to 7.0 % ( P < 0.01 ) and Ox-LDL induced expression of ICAM-1 ( 75 % ) and P-selectin ( 72 % ). mAbs to ICAM -1 or P-selectin, when used alone, could only slightly reduce the adhesion of monocyte to HUVEC
Chen et al., J Mol Cell Cardiol 2003 : Ox-LDL markedly increased the expression of P-selectin and intracellular adhesion molecule-1 ( ICAM-1 ) ( both protein and mRNA ) in HCAECs, and enhanced the adhesion of monocytes to the cultured HCAECs ... Both EPA and DHA decreased ox-LDL induced upregulation of expression of P-selectin and ICAM-1, and the enhanced adhesion of monocytes to HCAECs
Kobayashi et al., Ther Apher Dial 2006 (Arterial Occlusive Diseases...) : LDL-apheresis reduces P-Selectin , CRP and fibrinogen -- possible important implications for improving atherosclerosis
Chen et al., Cell Biochem Biophys 2011 (MAP Kinase Signaling System) : The results showed that the pre-treatment with delphinidin ( 50, 100, or 200 µM ) dose-dependently decreased the ox-LDL induced up-regulation of the expression of ICAM-1 and P-selectin , and the enhanced adhesion and transmigration of monocytes ... These results suggest that delphinidin attenuates ox-LDL induced expression of adhesion molecules ( P-selectin and ICAM-1 ) and the adhesion of monocytes to endothelial cells by inhibiting ROS/p38MAPK/NF-?B pathway
Gebuhrer et al., Biochem J 1995 : In this study we have looked at the effect of native or oxidized LDL on the expression of P-selectin ... Results show that EC-LDL and Cu-LDL, but not N-LDL or C-LDL, induce the expression of P-selectin by human umbilical-vein endothelial cells ( HUVECs )
Li et al., Endothelium : journal of endothelial cell research 1998 : To elucidate the mechanisms of the inhibition on adhesion, PBC effects on the Ox-LDL induced expression of P-selectin , on the synthesis of von Willebrand factor (vWF) and prostacyclin ( PGI2 ) were examined ... PBC 25, 50 and 75 micromol/L inhibited the Ox-LDL induced adhesion index from 37.3 % to 19.7, 16.6 and 14.6 % respectively ( p all < 0.05 ), and inhibited the Ox-LDL induced expression of P-selectin from 293.0 ng/ml to 180.0, 132.9 and 132.6 ng/ml respectively ... This effect is associated with the inhibition of the Ox-LDL induced expression of P-selectin and the protection on the synthesis of PGI2