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CD14 — HNRNPF

Text-mined interactions from Literome

Caux et al., Blood 1997 : In response to granulocyte-macrophage colony stimulating factor plus tumor necrosis factor alpha, cord blood CD34+ hematopoietic progenitor cells differentiate along two unrelated dendritic cell ( DC ) pathways : ( 1 ) the Langerhans cells ( LCs ), which are characterized by the expression of CD1a, Birbeck granules, the Lag antigen, and E cadherin ; and ( 2 ) CD14+ cell derived DCs , characterized by the expression of CD1a, CD9, CD68, CD2, and factor XIIIa ( Caux et al, J Exp Med 184 : 695, 1996 )
Santiago-Schwarz et al., Blood 1998 : Cultures enriched in CD14 dependent DCs were more potent stimulators of a mixed leukocyte reaction, compared with control GTS cultures containing both types of DCs ... When exposed to the appropriate cytokine combinations, these cells yielded granulocytes, monocytes, and CD14 dependent DCs ... Although TNF is required to ensure the institution of DC hematopoiesis from CD34 ( + ) progenitor cells, its activity on a later progenitor appears to limit the development of CD14 dependent DCs