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CDKN1B — EPHB2

Text-mined interactions from Literome

Hu et al., Mol Biol Cell 2005 : ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway : implication of p27kip1 in cell response to oxidative stress
Villanueva et al., Mol Biol Cell 2007 : Mechanistic analysis showed that the ERK effect on p27kip1 is mediated by Skp2 and is secondary to its effect on cyclin D1
Grant et al., Mol Endocrinol 2008 : The SSTR2-selective agonist L-779,976 is more efficacious at inhibiting adenylate cyclase, activating ERK1/2 , and inducing the cyclin dependent kinase inhibitor p27 ( Kip1 ) in cells expressing both SSTR2 and SSTR5 compared with SSTR2 alone
Kress et al., Cell communication and signaling : CCS 2010 : High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells