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PKN1 — RAC1
Text-mined interactions from Literome
Torbett et al., J Biol Chem 2003
:
Hyperosmotic induced
protein kinase N 1 activation in a vesicular compartment is
dependent upon
Rac1 and 3-phosphoinositide dependent kinase 1 ...
PKN1 translocation is
dependent on
Rac1 activation, although the GTPase binding HR1abc domain is not sufficient for this recruitment ... Taken together, our findings present a pathway for the selective hyperosmotic induced
Rac1 dependent
PKN1 translocation and PDK1 dependent activation
Bourguignon et al., J Biol Chem 2004
(Calcium Signaling) :
Hyaluronan-CD44 interaction with
Rac1 dependent
protein kinase N-gamma promotes phospholipase Cgamma1 activation, Ca ( 2+ ) signaling, and cortactin-cytoskeleton function leading to keratinocyte adhesion and differentiation