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GALP — LEP

Text-mined interactions from Literome

Krasnow et al., Endocrinology 2003 (Body Weight) : GALP neurons in the arcuate nucleus coexpress leptin receptors, and GALP mRNA expression is up-regulated by leptin
Kumano et al., Endocrinology 2003 (Disease Models, Animal...) : The result supports the hypothesis that the hypothalamic GALP gene expression is controlled by leptin signals and suggests possible involvement of GALP in the reproductive abnormalities of the Zucker obese rat
Hansen et al., Endocrinology 2003 (Body Weight...) : Galanin-like peptide (GALP) , a recently described hypothalamic neuropeptide, is up-regulated by leptin and has anorectic effects in the mouse ... We postulated that GALP mediates effects of leptin upon metabolism ... These observations suggest that leptin 's activation of the sympathetic nervous system, and ultimately thermogenesis, may be partially mediated by GALP through a melanocortin independent mechanism
Seth et al., Endocrinology 2004 : Galanin-like peptide stimulates the release of gonadotropin releasing hormone in vitro and may mediate the effects of leptin on the hypothalamo-pituitary-gonadal axis
Stoyanovitch et al., Diabetes 2005 (Body Weight...) : Galanin-like peptide (GALP) is expressed in the hypothalamic arcuate nucleus and is regulated by leptin and insulin
Rich et al., Physiol Behav 2007 (Body Weight) : After 2 weeks, GALP infusion had no significant effect on the onset of puberty, percent body fat, nor plasma levels of insulin, FSH or gonadal steroids in either sex ; however, GALP did significantly ( p < 0.05 ) increase plasma levels of LH and leptin in male but not female rats and increased plasma growth hormone (GH) in both sexes