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AHSA1 — RAC1
Text-mined interactions from Literome
Jeong et al., FEBS Lett 2002
:
The analysis of mitogen activated protein kinase activity indicated that
V12-Rac1 expression
led to a decrease in
p38 activity after exposure to cisplatin but not c-jun N-terminal kinase and extracellular signal regulated kinase
Woo et al., Mol Cells 2002
(MAP Kinase Signaling System) :
Rac GTPase activity is
essential for lipopolysaccharide signaling to extracellular signal regulated kinase and
p38 MAP kinase activation in rat-2 fibroblasts
Dunford et al., J Bone Miner Res 2006
:
Paradoxically, although risedronate induces apoptosis of J774 macrophages by inhibiting protein prenylation, the p38 inhibitor SB203580 enhanced N-BP induced apoptosis, suggesting that
Rac induced
p38 activation partially suppresses the pro-apoptotic effect of N-BPs in these cells
Zhang et al., J Biol Chem 2009
(Breast Neoplasms...) :
Rac1 blockade
inhibits p38/JNK kinase activities and the spontaneous anoikis of D4-GDI knockdown cells
Verma et al., Cardiovasc Res 2011
(Mechanotransduction, Cellular) :
These results indicate that stretch induced activation of
Rac1 and RhoA differentially
regulates Ao gene expression by modulating
p38 and JNK activation
Shifrin et al., Biochem J 2012
(Mechanotransduction, Cellular) :
Apoptosis was mediated by
Rac dependent activation of
p38a
Zohn et al., Mol Cell Biol 1998
(Cell Transformation, Neoplastic) :
Fourth, Mas and
Rac1 strongly
activated the JNK and
p38 , but not ERK, mitogen activated protein kinases