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EGF — MAP2

Text-mined interactions from Literome

Yan et al., Cell Biol Int 2005 : EGF+bFGF had a greater effect on MAP2 mRNA expression than EGF or bFGF alone
Smith et al., J Neurochem 1989 (Adrenal Gland Neoplasms...) : Treatment of PC12 cells with MTA inhibited NGF-, but not EGF mediated activation of MAP2/pp250-kinase ( Ki greater than 500 microM )
Hoshi et al., Eur J Biochem 1989 : Down-regulation of protein kinase C by prolonged phorbol ester treatment abolished the MAP2 kinase activation by phorbol ester, but did not prevent the MAP2 kinase activation by epidermal growth factor (EGF) or fresh serum
Hoshi et al., J Biol Chem 1988 : The half-maximal activation of the kinase activity occurred within 5 min after EGF treatment, and the maximal level was attained at 15 min. Casein and histone were very poor substrates for this EGF stimulated MAP2 kinase activity ... Interestingly, the EGF stimulated MAP2 kinase activity was sensitive to micromolar concentrations of free Ca2+ ; it was inhibited 50 % by 0.5 microM Ca2+ and almost totally inhibited by 2 microM Ca2+