◀ Back to MAPK1
ABCB1 — MAPK1
Text-mined interactions from Literome
Osborn et al., Oncogene 1999
:
Therefore, we examined the potential
role of
MAPK activation in TPA mediated
MDR1 induction in human leukemia K562 cells
Tao et al., Biomed Pharmacother 2013
:
In the present study, we show that paclitaxel induces
MDR1 expression in the MCF-7 breast cancer cell line in a
MAPK/Egr-1 dependent manner ... These findings suggest that
Erk1/2 induced Egr-1 accumulation
activates MDR1 transcription and thereby induces the drug resistance observed in paclitaxel-resistant MCF-7 cells