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PI3 — TNFSF10

Text-mined interactions from Literome

Musgrave et al., Exp Cell Res 1999 : The PKC inhibitors staurosporine and calphostin C, and the phosphatidylinositol 3-kinase (PI3-K) inhibitors wortmannin and LY294002, also prevented TRAIL mRNA transcription by activated T cells, indicating a role for PKC and PI3-K
Beresford et al., J Interferon Cytokine Res 2001 (Prostatic Neoplasms) : Suppression of PI3'-kinase/Akt signaling markedly enhanced the apoptotic activity of both TNF and TRAIL in LNCaP cells but not in PC-3 cells
Wang et al., J Biol Chem 2002 : Activation of PI 3-kinase by pretreatment with IGF-1, a gut trophic factor, markedly attenuated the induction of TRAIL by wortmannin ... Taken together, our findings demonstrate induction of the TRAIL by inhibition of PI 3-kinase in colon cancer cell lines
Milani et al., J Neurochem 2003 (Neuroblastoma) : Moreover, TRAIL increased CREB phosphorylation and phospho-CREB DNA binding activity in a phosphatidylinositol 3-kinase (PI 3K)/Akt dependent manner
Balzarolo et al., Eur J Immunol 2012 : Furthermore, PI3K signaling is required for NAB2 mediated TRAIL expression