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IL1RAP — IL33

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Innatedb Interaction: Complex of IL33-IL1RL1-IL1RAP-IL1RAP-IL1RL1-IL33 (unknown, -) Lingel et al., Structure 2009*

Text-mined interactions from Literome

Ali et al., Proc Natl Acad Sci U S A 2007 : IL-33 activates IL-1 receptor associated kinase-1, cJun-N-terminal kinase, and the NF-kappaB pathway in an IL-1RAcP dependent manner and results in IL-2 release
Palmer et al., Cytokine 2008 : The IL-1 receptor accessory protein ( AcP ) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33
Hong et al., Immunol Res 2013 : IL-33 receptor complex is comprised of IL-1 receptor accessory protein ( IL-1RAcP ) and ST2 that are activated by IL-33 ligand binding
Korherr et al., Eur J Immunol 1997 : A critical role for interleukin-1 receptor accessory protein in interleukin-1 signaling