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GRM1 — PRKACG

Text-mined interactions from Literome

Miyashita et al., Receptors Channels 2000 (MAP Kinase Signaling System) : Taken together, we concluded that the Ca2+o sensing function of mGluR1alpha and the continuous stimulation by Ca2+o caused the increase in the basal cAMP level by direct coupling with Gs, and triggered the subsequent activation of PKA , MAPKK, and MAPK cascade which resulted in the morphological change of transfected CHO cells
Mundell et al., Mol Pharmacol 2004 : In coimmunoprecipitation experiments, the ability of glutamate to increase association of GRK2 and arrestin-2 with mGluR1a and mGluR1b was inhibited by PKA activation with forskolin ... Together, these results indicate that PKA activation inhibits the agonist induced internalization and desensitization of mGluR1a and mGluR1b , probably by reducing their interaction with GRK2 and nonvisual arrestins