Gene interactions and pathways from curated databases and text-mining

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F2R — PLA2G4A

Text-mined interactions from Literome

Buresi et al., FASEB J 2002 : PAR-1 induced activation of cPLA2 , as shown by Western blot of phosphoserine residues, was blocked in cells treated with the MEK inhibitor U0126, indicating that the MEK-ERK1/2 MAP kinase pathway mediated PAR-1 induced cPLA2 phosphorylation
Gluck et al., Am J Physiol Cell Physiol 2008 : However, the PAR-1 inhibitor did not prevent thrombin induced mRNA expression of cPLA2 and LPAAT, implying that the activation of cPLA2 and LPAAT is essential but not sufficient for thrombin induced proliferation of BASMCs