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PPP1R13L — TP53

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: TP53 → PPP1R13L (decreases, PPP1R13L Activity) Bergamaschi et al., Nat Genet 2003*
  Evidence: iASPP is an evolutionarily conserved inhibitor of p53; inhibition of iASPP by RNA-mediated interference or antisense RNA in C. elegans or human cells, respectively, induces p53-dependent apoptosis.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind_translation Interaction: PPP1R13L — TP53 (coimmunoprecipitation) Issaeva et al., Nat Med 2004*
• IRef Biogrid Interaction: PPP1R13L — TP53 (physical association, affinity chromatography technology) Bergamaschi et al., Nat Genet 2003*
• IRef Dip Interaction: PPP1R13L — TP53 (direct interaction, solid phase assay) Robinson et al., Structure 2008*
• IRef Hprd Interaction: PPP1R13L — TP53 (in vitro) Bergamaschi et al., Nat Genet 2003*
• IRef Intact Interaction: PPP1R13L — TP53 (physical association, anti bait coimmunoprecipitation) Mantovani et al., Nature structural & molecular biology 2007*
• IRef Intact Interaction: PPP1R13L — TP53 (physical association, anti bait coimmunoprecipitation) Lu et al., Cancer Cell 2013*
• IRef Intact Interaction: PPP1R13L — TP53 (colocalization, fluorescence microscopy) Lu et al., Cancer Cell 2013*
• IRef Intact Interaction: PPP1R13L — TP53 (physical association, pull down) Lu et al., Cancer Cell 2013*
• IRef Intact Interaction: Complex of TP53-EP300-PPP1R13L (association, anti bait coimmunoprecipitation) Gillotin et al., FEBS Lett 2011*