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MMP14 — TP53
Text-mined interactions from Literome
Sun et al., Mol Carcinog 1999
(Neoplasm Metastasis) :
p53 transcriptionally
activates expression of the genes encoding epidermal growth factor receptor,
matrix metalloproteinase (MMP)-2 , cathepsin D, and thrombospondin-1 but represses expression of the genes encoding basic fibroblast growth factor and multidrug resistance-1
Abd El-Aziz et al., Cancer Sci 2007
:
Treatment of MCF7 cells with GDF15
induced activation of
p53 and enhanced expression of p21, which was abrogated by
MT1-MMP expression
Xiao et al., J Cell Biochem 2009
(Melanoma) :
Cytoprotective effects of the lipoidic-liquiform pro-vitamin C tetra-isopalmitoyl-ascorbate ( VC-IP ) against ultraviolet-A ray induced injuries in human skin cells together with collagen retention,
MMP inhibition and
p53 gene repression