Gene interactions and pathways from curated databases and text-mining

◀ Back to SNRPA1

SNRPA — SNRPA1

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • IRef Biogrid Interaction: SNRPA — SNRPA1 (colocalization, biochemical) Havugimana et al., Cell 2012
  • IRef Biogrid Interaction: SNRPA — SNRPA1 (direct interaction, two hybrid) Hegele et al., Mol Cell 2012
  • MIPS CORUM CDC5L complex: CDC5L complex complex (BCAS2-BZW1-CDC5L-CWC15-DYNC1H1-GCN1L1-HSPA8-ILF2-PLRG1-PPM1D-PPP1CA-PRKDC-PRPF19-SCAF8-RBMX-SF3B1-SF3B2-SF3B4-SFI1-SFPQ-SRSF1-SRSF2-SNRPA-SNRPA1-SNRPD1-SNRPD2-SNRPD3-SRRM1-TCF4-TOP2A) Ajuh et al., EMBO J 2000
  • MIPS CORUM Spliceosome: Spliceosome complex (ACIN1-AQR-DDX39B-BCAS2-BUD13-BUD31-CFAP20-CACTIN-C19orf43-CD2BP2-CDC40-CDC5L-CIRBP-CPSF6-CDK12-CRNKL1-LUC7L3-CTNNBL1-CWC15-CWC22-DDX17-DDX23-DDX3X-DDX41-DDX46-DDX5-DGCR14-DHX15-DHX16-DHX38-DHX8-DHX9-DNAJC8-EFTUD2-EIF4A3-PAXBP1-HTATSF1-IGF2BP3-IK-ISY1-KIAA1429-LSM2-LSM3-LSM4-LSM6-LSM7-MAGOH-MFAP1-MOV10-NCBP1-NCBP2-NHP2L1-NUDT21-PABPC1-PLRG1-PPIE-PPIH-PPIL1-PPIL2-PPIL3-PPM1G-PPWD1-PRPF18-PRPF19-PRPF3-PRPF31-PRPF4-PRPF40A-PRPF4B-PRPF6-PRPF8-PUF60-RBM15-RBM17-RBM22-RBM25-RBM39-RBM8A-RNPS1-SART1-SF1-SF3A1-SF3A2-SF3A3-SF3B1-SF3B6-SF3B2-SF3B3-SF3B4-SRSF1-SRSF11-SRSF2-SRSF3-SRSF4-SRSF5-SRSF7-SKIV2L2-SLU7-SMNDC1-SMU1-SNRNP200-SNRNP27-SNRNP40-SNRNP70-SNRPA-SNRPA1-SNRPB-SNRPB2-SNRPC-SNRPD1-SNRPD2-SNRPD3-SNRPE-SNRPF-SNRPG-SNW1-SPEN-U2SURP-SRRM1-SRRM2-SRRT-SRSF6-SRSF9-SYF2-TCERG1-TFIP11-THOC1-THOC2-THOC3-ALYREF-THOC5-THOC6-THOC7-TRA2B-TXNL4A-U2AF1-U2AF2-USP39-WBP11-WTAP-XAB2-ZNF207) Zhou et al., Nature 2002
  • IRef Corum Interaction: Complex of 61 proteins (association, coimmunoprecipitation) Ajuh et al., EMBO J 2000
  • IRef Corum Interaction: Complex of 427 proteins (association, molecular sieving) Zhou et al., Nature 2002
  • IRef Intact Interaction: SNRPA — SNRPA1 (physical association, two hybrid) Hegele et al., Mol Cell 2012
  • IRef Intact Interaction: Complex of 30 proteins (association, anti tag coimmunoprecipitation) Pichlmair et al., Nat Immunol 2011
  • IRef Intact Interaction: Complex of 33 proteins (association, anti tag coimmunoprecipitation) Pichlmair et al., Nat Immunol 2011
  • IRef Intact Interaction: Complex of 36 proteins (association, anti tag coimmunoprecipitation) Pichlmair et al., Nat Immunol 2011

Text-mined interactions from Literome

Daugeron et al., Nucleic Acids Res 1992 : Moreover, RNAse T1 protection coupled to immunoprecipitation experiments have demonstrated that only the 5 ' end sequence of U1 snRNA contacts the consensus 5 ' splice site containing RNA, arguing that U2 snRNP binding in the tripartite complex is mediated by U1 snRNP
Fu et al., Proc Natl Acad Sci U S A 1992 : Significantly, the SC35 dependent interaction between U1 snRNP and the 3 ' splice site requires U2 snRNP but not the 5 ' splice site
Gräub et al., Cell cycle (Georgetown, Tex.) 2008 : We also demonstrate that a specific inhibitor of CDK2 , CVT-313, inhibits CDC5L phosphorylation in both in vitro kinase assays and in vivo radiolabeling experiments in cycling cells
Martins de Araújo et al., RNA 2009 (Muscular Atrophy, Spinal) : Two trans acting factors implicated in SMN regulation , SF2/ASF and hnRNP A1, promote and repress, respectively, U2 snRNP recruitment to both RNAs
Urano-Tashiro et al., J Neurosci Res 2010 : Implication of Akt dependent Prp19 alpha/14-3-3beta/Cdc5L complex formation in neuronal differentiation ... Here, we demonstrated that PRP19 alpha/14-3-3beta/CDC5L complex formation is regulated by Akt during nerve growth factor (NGF) induced neuronal differentiation of PC12 cells
Blencowe et al., Genes Dev 1998 (Lymphoma, Large B-Cell, Diffuse) : Binding of SRm160/300 to pre-mRNA is normally also dependent on U1 snRNP and is stabilized by U2 snRNP