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CEBPB — CREB3
Text-mined interactions from Literome
Zhang et al., J Biol Chem 2004
:
Role of
CREB in transcriptional regulation of
CCAAT/enhancer binding protein beta gene during adipogenesis ... Consistent with the interaction of CREB and ATF1 at the TGA regulatory elements, expression of constitutively active
CREB strongly
activated C/EBPbeta promoter-reporter genes, induced expression of endogenous C/EBPbeta, and caused adipogenesis in the absence of the hormonal inducers normally required ... Conversely, expression of a dominant negative
CREB blocked promoter-reporter activity, expression of
C/EBPbeta , and adipogenesis
Fox et al., J Biol Chem 2006
:
Depletion of
CREB/ATF1 did not
suppress the expression of
C/EBP beta as we had previously observed using dominant negative forms of CREB
Karamitri et al., J Biol Chem 2009
:
Forskolin stimulation and
C/EBPbeta overexpression in 3T3-L1 cells
increased C/EBPbeta and
CREB but displaced ATF-2 and CHOP10 binding to the Pgc-1alpha proximal CRE
Ruffell et al., Proc Natl Acad Sci U S A 2009
:
CREB mediated induction of
Cebpb expression is therefore required in infiltrating macrophages for upregulation of M2-specific genes and muscle regeneration, providing a direct genetic link between these two processes