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DUSP1 — EGF

Text-mined interactions from Literome

Seta et al., J Biol Chem 2001 (Anoxia) : The magnitude of the effect of hypoxia on MKP-1 was approximately equal to that induced by KCl depolarization and much larger than the effects of either epidermal growth factor or nerve growth factor on MKP-1 mRNA levels
Ryser et al., Biochem J 2004 (MAP Kinase Signaling System) : In the pituitary cell line GH4C1, MKP-1 gene transcription is strongly induced by thyrotropin releasing hormone (TRH) as well as by epidermal growth factor (EGF) as a consequence of activated MAPK/extracellular-signal regulated kinase ( ERK ) signalling
Wang et al., Invest Ophthalmol Vis Sci 2006 : After 1 hour, EGF induced 14-fold increases in MKP-1 protein expression
Sarközi et al., J Cell Physiol 2007 : The EGF mediated time dependent induction of MKP-3, MKP-1 and DUSP5 mRNA levels was U0126-sensitive at a concentration, which blocked EGF mediated ERK1/2 phosphorylation but not ERK5 phosphorylation ... Furthermore, U0126 inhibited EGF induced MKP-3 and MKP-1 protein expression
Machado et al., J Neurosci Res 2008 (MAP Kinase Signaling System) : Nerve growth factor and epidermal growth factor are unable to induce the expression of the Crem/Icer, Nur77, Nor1, Rgs2, Dusp1 ( Mkp1 ), and Dscr1 genes in PC12 cells, validating their identification as IPD-IEGs
Chandrasekharan et al., Arterioscler Thromb Vasc Biol 2010 : EGF alone did not induce MKP-1 substantially ( < 2-fold ) ... The EGF receptor kinase inhibitor AG1478 blocked approximately 70 % of MKP-1 induction by thrombin plus EGF ( from 18- to 6-fold ) but not the response to thrombin alone ... Inhibitors of extracellular signal regulated kinase and JNK activation blocked thrombin plus EGF induced MKP-1 completely
Reuter et al., PloS one 2012 (Inflammation...) : These differences in epithelial restitution were TGF-ß independent but Dex inhibited the EGF/ERK1/2/MAPK-pathway important for intestinal epithelial wound healing by induction of MKP-1 and Annexin-1 which was not affected by CpdA or ZK216348
Cook et al., J Biol Chem 1997 : Activation of PKC played little part in growth factor stimulated MKP-1 expression, but LPA- and EGF induced MKP-1 expression was blocked by buffering [ Ca2+ ] i, leading to a potentiation of the sustained phase of ERK1 activation without potentiating MEK activity