Gene interactions and pathways from curated databases and text-mining

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MAPK1 — NTF4

Text-mined interactions from Literome

Vesa et al., J Biol Chem 2000 : p75 did not effect extracellular signal regulated kinase 2 tyrosine phosphorylation in response to brain derived neurotrophic factor, neurotrophin 3, or neurotrophin 4/5
Wiklund et al., J Neurobiol 2000 : In conclusion, the data suggest that NT-4 can serve as a powerful growth factor for neurons of adult nodose ganglia and that the growth stimulation involves TrkB- and mitogen activated protein kinase
Shi et al., Cell Signal 2006 : Dok5 is substrate of TrkB and TrkC receptors and involved in neurotrophin induced MAPK activation
Moubarak et al., J Neurosci 2010 : Altogether, we uncover a new role for FLIP-L as an unexpected critical player in neurotrophin induced mitogen activated protein kinase/ERK- and NF-kappaB mediated control of neurite growth in developing neurons
White et al., Br J Cancer 2010 (Sarcoma, Ewing) : Sustained p38 ( MAPK ) phosphorylation upregulates p75 neurotrophin ( p75 ( NTR ) ) and induces apoptosis in Ewing 's sarcoma family of tumours ( ESFT )
Guiton et al., J Biol Chem 1995 : In cells expressing full-length TrkC, neurotrophin-3 promoted a sustained activation of mitogen activated protein kinase ; TrkC containing kinase inserts only mediated transient activation of mitogen activated protein kinase