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IL6 — WNT5A

Text-mined interactions from Literome

Blumenthal et al., Blood 2006 (Inflammation...) : Functional studies showed that WNT5A and FZD5 regulate the microbially induced interleukin-12 response of antigen presenting cells and interferon-gamma production by mycobacterial antigen stimulated T cells
Katoh et al., Int J Mol Med 2007 (Arthritis, Rheumatoid...) : IL6 , secreted from epithelial cells or macrophages, induces WNT5A upregulation in mesenchymal cells ... IL6 induced WNT5A activates canonical WNT signaling for autocrine proliferation of human synovial fibroblasts in rheumatoid arthritis
Katoh et al., Cancer Biol Ther 2007 (Helicobacter Infections...) : IL-6 and TNFalpha induce upregulation of WNT5A and WNT10B, respectively
Li et al., J Biol Chem 2013 (MAP Kinase Signaling System) : We show that inhibition of Wnt5a by specific antagonists blocks gp120 induced up-regulation of IL-1ß, IL-6 , and TNF-a in the spinal cord
Oderup et al., J Immunol 2013 : Moreover, although both Wnts suppress proinflammatory responses to bacterial endotoxin and to TLR1/2, TLR7, and TLR9 ligands, Wnt5A , but not Wnt3A, inhibits IL-6 production in response to the viral mimic, polyinosinic : polycytidylic acid