◀ Back to RAC1
NOXO1 — RAC1
Pathways - manually collected, often from reviews:
-
NCI Pathway Database RAC1 signaling pathway:
RAC1/GTP complex (RAC1)
→
RAC1/GTP/NOX1/NOXA1/NOXO1 complex (RAC1-NOX1-NOXA1-NOXO1)
(modification, collaborate)
Cheng et al., J Biol Chem 2006, Miyano et al., J Biol Chem 2006*
Evidence: assay, physical interaction
-
NCI Pathway Database RAC1 signaling pathway:
RAC1/GTP complex (RAC1)
→
NOX1/NOXA1/NOXO1 complex (NOX1-NOXA1-NOXO1)
(modification, collaborate)
Cheng et al., J Biol Chem 2006, Miyano et al., J Biol Chem 2006*
Evidence: assay, physical interaction
-
NCI Pathway Database RAC1 signaling pathway:
RAC1/GTP/NOX1/NOXA1/NOXO1 complex (RAC1-NOX1-NOXA1-NOXO1)
→
NOX1/NOXA1/NOXO1 complex (NOX1-NOXA1-NOXO1)
(modification, collaborate)
Cheng et al., J Biol Chem 2006, Miyano et al., J Biol Chem 2006*
Evidence: assay, physical interaction
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Kawahara et al., Am J Physiol Cell Physiol 2005
:
Thus the H. pylori LPS stimulated O2- production in gastric mucosal cells appears to require two distinct events : 1 ) transcriptional upregulation of Nox1 and
NOXO1 and 2 )
activation of
Rac1
Cheng et al., J Biol Chem 2006
:
Rac1 ( G12V ) interaction with NOXA1 was
enhanced by Nox1 and
NOXO1 , suggesting cooperative binding