Gene interactions and pathways from curated databases and text-mining

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BAX — IL24

Text-mined interactions from Literome

Cao et al., Mol Med 2002 (Mesothelioma) : Adenoviral transfer of mda-7 leads to BAX up-regulation and apoptosis in mesothelioma cells, and is abrogated by over-expression of BCL-XL
Chada et al., Mol Ther 2004 (Melanoma) : MDA-7 receptor engagement results in up-regulation of BAX and subsequent apoptosis induction ; this effect is mediated by STAT3 independent signaling
Zhuo et al., Tumour Biol 2013 (Neuroblastoma) : To further explore the molecular mechanism by which Ad-IL24 induced apoptosis in SH-SY5Y tumor cells, we found that Ad-IL24 increased the expression of Bax and promoted the activation of caspase-3, while decreasing Bcl-2 levels