Gene interactions and pathways from curated databases and text-mining

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PARP1 — RASGRP3

Text-mined interactions from Literome

Regier et al., Proc Natl Acad Sci U S A 2005 (Neoplasms, Experimental) : In addition to activating Ras, RasGRP3 also activates Rap1 , which in some cases can antagonize the function of Ras ... In addition to activating Ras, RasGRP3 also activates Rap1 , which in some cases can antagonize the function of Ras
Ikuta et al., Cancer Res 2008 (Dermatitis, Contact...) : Experiments using small interfering RNA mediated knockdown indicate that this activation is mediated by Rap1 , which is activated by a TPA-responsive guanine nucleotide exchange factor RasGRP3
Takino et al., Cell Adh Migr 2013 : Furthermore, RasGRP2 overexpression increased Rap1 activation and cell-matrix adhesion in ECV304 cells